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For example, in colorectal cancer (CRC), tumor-derived lanosterol can be taken up by CD8⁺ T cells, where it suppresses the mevalonate pathway and reduces prenylation and activity of KRAS proto-oncogene, GTPase (KRAS), ultimately promoting T cell apoptosis and impairing their antitumor function
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From there, it was found that treatment with BPC 157 in the experimental groups led to consistent improvement in motor function in comparison to the control groups
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