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Example 25 Comparison of changes with time in the concentration of the glutathione derivative in the blood when the fat emulsion of a glutathione derivative having a long-chain ester having 12 carbons or more and the aqueous solution of Comparative Example 1 and the fat emulsion of Comparative Example 2 were intravenously administered to rabbits Example 4-fat emulsion administration group that received 20 mg/kg-body weight/day or higher was shown to have a dose-dependent effect of promoting the recovery of neutrophil counts in the rat models of suppressed hematopoietic function by 5-FU administration, and in the Example 4-fat emulsion administration group that received 30 mg/kg-body weight/day was shown to have an effect of promoting the recovery of neutrophil counts that is almost equal to that of the G-CSF 10 ⁇ g/kg-body weight/day administration group

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[DOI] [PubMed] [Google Scholar] 27.Frye R.E., Slattery J., Delhey L., Furgerson B., Strickland T., Tippett M., Sailey A., Wynne R., Rose S., Melnyk S., et al