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The net effect is bidirectional matrix turnover rather than one-way collagen accumulation
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Keywords: GHK peptide, fibroblasts, myofibroblasts, senescence, fibrosis, idiopathic pulmonary fibrosis The loss of cellular homeostasis in fibrosis is characterized by the accumulation of activated fibroblasts, known as myofibroblasts [1], which are responsible for excessive extracellular matrix deposition and tissue remodeling
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