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Single doses of 42, 140, 420 and 1260 mg intravenously were well tolerated and showed dose-proportional, linear pharmacokinetics, with the half-life increasing with the dose Ruff et al., 2010
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We demonstrated that, although ROS are necessary for the initiation phase of ATG, the modulation of thiols are fundamental for the progression of starvation-induced ATG (Desideri et al., 2012
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