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And if itโs significantly elevated above optimal (ideal is typically in the 6-8 nmol/mL range), a high-quality B-vitamin supplements can reduce homocysteine aggressively
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APE1, as a DNA repair enzyme, has the ability to regulate epithelial ROS by regulating the interaction of Rac1 and Nox1, which, in turn, inhibits the production of NADPH oxidase, thus reducing the level of ROS (den Hartog et al., 2016)
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