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LLO requires a 30–40 mol% Chol threshold in the lipid membrane for effective binding and pore formation (Decatur and Portnoy (2000) have identified a relevant region within listeriolysin O, the so-called PEST-like region (P: proline, E: glutamine, S: serine, T: teronine)
Vitamin
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Dimercaprol is administered in combination with sodium calcium edetate and should be administered as first aid at a site different from that of the edetate
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