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In recent years, 5‑Amino‑1MQ Peptide (abbreviated as 5‑Amino‑1MQ), a highly selective small‑molecule peptide inhibitor targeting nicotinamide N‑methyltransferase (NNMT), has exhibited broad application prospects and become a research hotspot in obesity and adipose tissue research due to its unique mechanism, favorable targeting ability, and safety

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Figure 2 GPR109A Protein Expression The interaction effect in the two-way Time × Group mixed ANOVA was significant, F (4,72) = 3.06, p = 0.022