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Article: Fatal hyperammonaemia due to late-onset ornithine transcarbamylase deficiency (full text) - January 2016 - NJM
In the proteomics data, both the siMAT2A group and the AG-270 group exhibited significant downregulation of lipid metabolism and MAT2A-related carbon metabolism, and the AG-270 group exhibited significant downregulation of glycolysis and upregulation of serine metabolism (Figures 2B, 2C, 2E and 2F)
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Ultimately, the study determined that the type of excess sugar does influence hepatic lipid metabolism and influences the advancement of NAFLD, therefore it is advisable to limit the consumption of HFCS and sweetened beverages containing calories
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