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In contrast, JARID1A interacts directly with CLOCK-BMAL1 and is involved in regulating circadian gene expression, with additional functions impacting HDAC1 recruitment without altering H3K4me3 methylation
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Thus, in a study of genetic variants in the GPx-1 locus in a Japanese population, a total of three major haplotypes were identified that involve two SNPs in transcriptional regulatory regions in combination with the Ala repeat and codon 198 polymorphism (152)
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