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Consistently, in vivo quantitative analysis showed that only ~26.7% of MnLR was released within 4 hours in the stomach, whereas release markedly accelerated during gastrointestinal transit (4–10 hours) and intestinal residence (10–20 hours), with cumulative release reaching ~83.5% within 20 hours (Fig

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Initial inflammatory responses triggered by adipose expansion become self-sustaining through multiple feedback loops