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Figure 17: Large Tophus Seen as Soft Tissue Mass at the Elbow ) but in special cases, such as when gout needs to be separated from infection or tumor, magnetic resonance imaging (MRI) ( Figure 18: MRI of the Knee Showing Gouty Soft Tissue Mass and Erosion of the Kneecap ) or ultrasound ( Figure 19: Power Doppler Study Showing Gouty Inflammation at the Base of the 1st Toe ) will be helpful
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For example, persistent inflammation can increase oxidative stress and metabolic demand, potentially complicating: Undermethylation Elevated SAH Zinc depletion Antioxidant requirements Glutathione demand Mitochondrial function hs-CRP is therefore useful as a broader context marker rather than as a Walsh biotype test by itself
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