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Astrocytes control CNS damage: neurotrauma, stroke, neuroinfection and autoimmune attack Neurotrauma Acute focal traumatic brain injury Acute focal traumatic brain injury (TBI) can be caused by penetrating lesions to the brain parenchyma that trigger cell death and haemorrhage, or by external force impact against the head resulting in brain contusion with intra-parenchymal haemorrhage, cell death and axonal damage
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