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elegans : Caenorhabditis elegans CHOP: C/EBP homologous protein cDNA: Complementary DNA DAF-2: Dauer larva formation abnormal 2 DEG: Differentially expressed gene DMSO: Dimethyl sulfoxide DMEM: Dulbecco’s modified eagle medium ER: Endoplasmic reticulum ERAD: Endoplasmic reticulum–associated degradation pathway FBS: Fetal bovine serum FUdR: 5-Fluoro-2′-deoxyuridine GAPDH: Glyceraldehyde-3-phosphate dehydrogenase GO: Gene ontology GRP78: Glucose-regulated protein 78 HSE: Heat shock element HSF-1/HSF1: Heat shock factor 1 HSPA1A: Heat shock protein family A (Hsp70) member 5 HSPA5: Heat shock protein family A (Hsp70) member 5 HSP: Heat shock protein HSP-3/HSP-4: Heat shock protein 3/4 HSP70: Heat shock protein 70 HSR: Heat shock response conserved cytoplasmic proteostasis pathway HT-1080: Human fibrosarcoma cell line HEK-293T: Human embryonic kidney 293T cell line IGF-1: Insulin-like growth factor 1 IRE-1: Inositol-requiring enzyme 1 KRIBB11: HSF1 inhibitor compound mRNA: Messenger RNA NGM: Nematode growth medium PBS: Phosphate buffered saline PDIA3: Protein disulfide isomerase family A member 3 PEK-1/PERK: Protein kinase RNA-like endoplasmic reticulum kinase qPCR: Quantitative polymerase chain reaction technique for measuring gene expression RNAi: RNA interference RT: Reverse transcription SERP1: Stress-associated endoplasmic reticulum protein 1 SPSS: Statistical package for the social sciences TIR1: Transport inhibitor response 1 TM: Tunicamycin UPR ER : Unfolded protein response of the endoplasmic reticulum WT: Wild type XBP-1/XBP1: X-box binding protein 1 References Hipp, M
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