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Researchers concluded that “a subgroup of [Alzheimer’s] patients aged 65 or younger may benefit from treatment with [ALCAR] whereas older individuals might do more poorly.” 13 A follow up study reanalyzed the results and came to similar conclusions, suggesting that ALCAR “slows the progression of Alzheimer’s disease in younger subjects.” 14 In another follow-up study that compared ALCAR’s effect on those with early-onset (age 45-65) and regular Alzheimer’s, researchers reached a different conclusion, reporting that “ there were no significant differences between the treatment groups.” 15 ALCAR 1,500 mg seems to help with depression in the elderly In this study, 28 elderly patients aged 70-80 who had been diagnosed with depression were given either 1,500 mg Acetyl-L-Carnitine or placebo daily, and were then evaluated with three cognitive tests and by clinical observation