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[6] In most cases where myopathy is present with MADD, a second muscle disease is present and symptoms are worse than either disease in isolation
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To remove senescent cells, these treatments induce apoptosis in SCs by inhibiting anti-apoptotic pathways mediated by Bcl-2 family proteins (e.g., Bcl-2 and Bcl-xL) and reduce the senescence-associated secretory phenotype (SASP) within senescent chondrocytes and synovial cells within the joint microenvironment, as shown in Fig
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