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Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreichβs Ataxia ( Trial number: NCT05302271 Overview: This study is testing the safety and early effects of a gene therapy called AAVrh.10hFXN, given through an IV, to treat heart problems caused by Friedreichβs ataxia, a genetic condition
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During the procedures, heart rate, blood pressure, respiratory rate, end tidal CO 2 , oxygen saturation, and temperature were monitored and adjusted to ensure appropriate planes of anesthesia
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