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Mucus that is high in viscosity or elasticity may require higher than normal air pressure and shear forces to dislodge or tear apart and so may be resistant to cough clearance as well as ciliary clearance (King, 1987
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a myostatin inhibitor e.g., a myostatin-selective inhibitor, e.g., an antibody or antigen-binding fragments thereof that specifically binds to pro/latent myostatin as described herein such as Ab109, Ab133, or Ab141 or a variant thereof additional therapy selected from one the use of the myostatin inhibitor may advantageously allow usage of lower dosages of a GLP-1 receptor agonist (e.g., semaglutide, liraglutide, tirzepatide, retatrutide), e.g., to avoid adverse events, toxicities, or other complications associated with use of the GLP-1 receptor agonist as a single agent
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US$40
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