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Local synthesis of these molecules within the tumor can promote dendritic cell activation, antigen presentation, macrophage repolarization, and cytotoxic T cell recruitment, converting immunologically “cold” gliomas into more inflamed lesions
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H3K4me3 is particularly associated with initiation of gene transcription, while H3K36me3 and H3K79me3 are associated with elongation of gene transcription
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