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Imeglimin amplifies glucose-stimulated insulin release from diabetic islets via a distinct mechanism of action (NAD+/CD38/cADPR)

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A team of Northwestern investigators led by Peter Penzes, PhD, the Ruth and Evelyn Dunbar Professor of Psychiatry and Behavioral Sciences and director of the Center for Autism and Neurodevelopment, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder (ASD), according to findings published in Molecular Psychiatry

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