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(54) found that RG107 increased the expression of DNMT1 in the DRG and that it did so via the activation of the transcription factor cAMP response element-binding protein (CREB), causing DNA methylation of the Kcna2 ( encoding Kv1.2 ) promoter, thereby reducing Kv1.2 expression and promoting pain
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QJM 112 , 387–388 (2019)
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