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Conclusions and Future Directions Endometriosis is a disease with significant heterogeneity

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Peptide therapy may benefit those who experience: Difficulty falling asleep or staying asleep Frequent night wakings Fatigue despite 7–8 hours in bed Jet lag or shift work-related sleep disturbances Sleep disruption from anxiety or high stress Hormonal imbalances (low GH, testosterone, melatonin) Aging-related decline in sleep quality Lifestyle and Supplement Synergy Peptides work best when paired with foundational sleep-supporting practices: Maintain a consistent bedtime and wake time Limit blue light exposure after sunset Avoid stimulants in the afternoon Incorporate magnesium, L-theanine, and GABA supplements Use adaptogens like ashwagandha or rhodiola to reduce cortisol Safety, Dosing, and Clinical Considerations Peptide therapy should always be administered under the supervision of a qualified provider