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For instance, the EXSCEL randomized placebo-controlled trial demonstrated that exenatide, a glucagon-like peptide receptor agonist, reduced inflammatory proteins associated with Alzheimer’s disease, which correlated with decreased levels of serum inflammatory markers ficolin-2, plasminogen activator inhibitor 1 (PAI-1), and soluble vascular cell adhesion protein 1 (sVCfAM1)
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