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oncogene-driven changes in the metabolism of glutathione Targeting Metabolism: Partner Crime in Anticancer Therapy Evening
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In comparison to the binding constants for cisplatin [ K = 8.52 × 10 2 M –1 (HSA)] 108 or KP1019 [ K = 10.6 × 10 4 M –1 (albumin) and 5.6 × 10 4 M –1 (transferrin)] 109 association with serum proteins, it was discovered that the total binding constant for the RAPTA-C–NCP ( K = 2.3 × 10 5 M –1 ) adducts was significantly larger
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