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Conversely, its knockdown in HepG2 cells leads to an increase in TG accumulation, a decrease in SIRT1 activity, and an increase in FASN and SREBP-1c, effects that can be reversed by resveratrol (Ilbeigi et al
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Determining the availability of metabolites in the lamina propria in conjunction with the microbiome, IECs might coordinate the recruitment of immune cells and guide immune cell functions to ensure efficient wound healing and barrier restitution upon mucosal injury
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