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The use of fluorescence spectroscopy to determine pK a values depends on the difference in the fluorescence spectrum between a free acid or base and its conjugated form
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Spermatozoa are susceptible to oxidative stress due to a lack of their own cellular cytoplasmic antioxidants, high DNA susceptibility to oxidative damage, the presence of abundant polyunsaturated fatty acids (PUFAs) in their membrane, and high ROS production during their movements, generated by mitochondrial activity (18, 85, 89, 118)
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