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Dysfunctional or insufficient HDL exacerbates oxidative damage and compromises BBB integrity, further facilitating the entry of neurotoxic substances and inflammatory mediators into the brain [49,50,51]
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Figure 2 Figure 3 2.3 Mevalonate pathway: a metabolic gatekeeper of ferroptosis The mevalonate (MVA) pathway—best known for cholesterol synthesis—is also a pivotal brake on ferroptosis
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