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There has been documented data indicating a potential link between low levels of 25-hydroxyvitamin D and cardiovascular disease (CVD), as well as possible processes behind these disorders
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NNMT as a target and the nicotinamide / NAD⁺ / methylation axis Nicotinamide N-methyltransferase (NNMT) is a cytosolic enzyme that transfers a methyl group from S-adenosylmethionine (SAM) on nicotinamide , forming 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH)
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